USP3 and PIC/S5 list supplemental things to be accomplished inside the OQ including cleansing and leak tests. Decontamination cycle growth occurs after the completion in the OQ and is discussed in detail in segment 6. Fresh new sterile air or nitrogen is circulated after decontamination. The H₂O�?vapor breaks down https://tailinscitech.weebly.com/blog/optimizing-pharma-filling-and-sealing-processes-with-tailin-technology