The causes of amyotrophic lateral sclerosis (ALS) are mostly undefined; however. excitotoxic injury and astrogliosis may contribute to motor neuron (MN) degeneration. Group I metabotropic glutamate (mGlu) receptors are over-expressed in reactive astrocytes in ALS. but the functional significance of this over-expression is presently unknown. https://www.hacklinkci.com/